Nipah Virus Transmission Dynamics: Zoonotic Origins, Human Spread, and Control Strategies
DOI:
https://doi.org/10.58222/juvokes.v3i2.1004Kata Kunci:
Nipah, Transmission, Pathology, Epidemiology, Control StrategiesAbstrak
A member of the Paramyxoviridae family, Nipah virus is one of the re-emerging viruses as a public health concern since it was first detected at the turn of the century in the late 1990s. Case fatality rates during outbreaks ranged between 40% and 75%, with recurrent cases in Bangladesh, India, and Malaysia. Surveillance data indicate the possibility of virus development in new areas since there is virus circulation among Pteropus bats in larger regions of South and Southeast Asia. It appears to be of zoonotic origin, transmitted mainly from fruit bats to humans. This makes zoonotic transmission a complex interaction between wildlife and human health, implying the significant role of ecology dynamics in the prevention and control of outbreaks. This understanding of routes of transmission has given basis to the devising of evidence-based interventions, including the protection of date palm sap collection sites and enhancement of infection prevention practices in hospitals, which will be very critical for controlling outbreaks and preventing future epidemics. This discussion on Nipah virus transmission dynamics calls for going into detail regarding the zoonotic source and mode of human-to-human transmission that enables human beings to prevent and control this disease.
Referensi
Amaya, Moushimi, and Christopher C. Broder. 2020. “Vaccines to Emerging Viruses: Nipah and Hendra.” Annual Review of Virology 7.
Bruno, Luigi, Maria Anna Nappo, Luca Ferrari, Rosanna Di Lecce, Chiara Guarnieri, Anna Maria Cantoni, and Attilio Corradi. 2023. “Nipah Virus Disease: Epidemiological, Clinical, Diagnostic and Legislative Aspects of This Unpredictable Emerging Zoonosis.” Animals 13(1).
Chaiyes, Aingorn, Prateep Duengkae, Warong Suksavate, Nantachai Pongpattananurak, Supaporn Wacharapluesadee, Kevin J. Olival, Kornsorn Srikulnath, Sura Pattanakiat, and Thiravat Hemachudha. 2022. “Mapping Risk of Nipah Virus Transmission from Bats to Humans in Thailand.” EcoHealth 19(2). doi: 10.1007/s10393-022-01588-6.
Epstein, Jonathan H., Simon J. Anthony, Ariful Islam, A. Marm Kilpatrick, Shahneaz Ali Khan, Maria D. Balkey, Noam Ross, Ina Smith, Carlos Zambrana-Torrelio, Yun Tao, Ausraful Islam, Phenix Lan Quan, Kevin J. Olival, M. Salah Uddin Khan, Emily S. Gurley, M. Jahangir Hossein, Hume E. Field, Mark D. Fielder, Thomas Briese, Mahmudur Rahman, Christopher C. Broder, Gary Crameri, Lin Fa Wang, Stephen P. Luby, W. Ian Lipkin, and Peter Daszak. 2020. “Nipah Virus Dynamics in Bats and Implications for Spillover to Humans.” Proceedings of the National Academy of Sciences of the United States of America 117(46). doi: 10.1073/pnas.2000429117.
Faus-Cotino, Javier, Gabriel Reina, and Javier Pueyo. 2024. “Nipah Virus: A Multidimensional Update.” Viruses 16(2).
Goh, Gerard Kian Meng, A. Keith Dunker, James A. Foster, and Vladimir N. Uversky. 2020. “Nipah Shell Disorder, Modes of Infection, and Virulence.” Microbial Pathogenesis 141. doi: 10.1016/j.micpath.2020.103976.
Hassan, Mohammad Mahmudul, Md Abul Kalam, Mahabub Alam, Shahanaj Shano, Abdullah Al Faruq, Md Saddam Hossain, Md Nurul Islam, Shahneaz Ali Khan, and Ariful Islam. 2020. “Understanding the Community Perceptions and Knowledge of Bats and Transmission of Nipah Virus in Bangladesh.” Animals 10(10). doi: 10.3390/ani10101814.
Hauser, Naomi, Alexis C. Gushiken, Shivakumar Narayanan, Shyam Kottilil, and Joel V. Chua. 2021. “Evolution of Nipah Virus Infection: Past, Present, and Future Considerations.” Tropical Medicine and Infectious Disease 6(1).
Joshi, Jagadish, Yogendra Shah, Kishor Pandey, Ram Prashad Ojha, Chet Raj Joshi, Lok Raj Bhatt, Shyam Prakash Dumre, Pushpa Raj Acharya, Hem Raj Joshi, Shikha Rimal, Ramesh Shahi, Deepak Pokharel, Kamal Singh Khadka, Bimal Dahal, Saroj Nepal, Ram Singh Dhami, Krishna Prasad Pant, Rajdip Basnet, and Basu Dev Pandey. 2023. “Possible High Risk of Transmission of the Nipah Virus in South and South East Asia: A Review.” Tropical Medicine and Health 51(1).
Letko, Michael, Stephanie N. Seifert, Kevin J. Olival, Raina K. Plowright, and Vincent J. Munster. 2020. “Bat-Borne Virus Diversity, Spillover and Emergence.” Nature Reviews Microbiology 18(8).
Liew, Yvonne Jing Mei, Puteri Ainaa S. Ibrahim, Hui Ming Ong, Chee Ning Chong, Chong Tin Tan, Jie Ping Schee, Raúl Gómez Román, Neil George Cherian, Won Fen Wong, and Li Yen Chang. 2022. “The Immunobiology of Nipah Virus.” Microorganisms 10(6).
Nikolay, Birgit, Henrik Salje, A. K. M. Dawlat Khan, Hossain M. S. Sazzad, Syed M. Satter, Mahmudur Rahman, Stephanie Doan, Barbara Knust, Meerjady Sabrina Flora, Stephen P. Luby, Simon Cauchemez, and Emily S. Gurley. 2020. “A Framework to Monitor Changes in Transmission and Epidemiology of Emerging Pathogens: Lessons from Nipah Virus.” Journal of Infectious Diseases 221. doi: 10.1093/INFDIS/JIAA074.
Orosco, Fredmoore L. 2023. “Advancing the Frontiers: Revolutionary Control and Prevention Paradigms against Nipah Virus.” Open Veterinary Journal 13(9).
Pillai, Vinod Soman, Gayathri Krishna, and Mohanan Valiya Veettil. 2020. “Nipah Virus: Past Outbreaks and Future Containment.” Viruses 12(4).
Singhai, Monil, Ruchi Jain, Sarika Jain, Manju Bala, Sujeet Singh, and Rajeev Goyal. 2021. “Nipah Virus Disease: Recent Perspective and One Health Approach.” Annals of Global Health 87(1). doi: 10.5334/aogh.3431.
Sun, Y. Q., Zhang, Y. Y., Liu, M. C., Chen, J. J., Li, T. T., Liu, Y. N., Zhang, L. Y., Wang, T., Yu, L. J., Che, T. L., Tang, T., Xu, Q., Lv, C. L., Jiang, B. G., Golding, N., Mehlman, M. L., Hay, S. I., Fang, L. Q., & Liu, W. (2024). Mapping the distribution of Nipah virus infections: a geospatial modelling analysis. The Lancet. Planetary health, 8(7), e463–e475. https://doi.org/10.1016/S2542-5196(24)00119-0
Alam A. M. (2022). Nipah virus, an emerging zoonotic disease causing fatal encephalitis. Clinical medicine (London, England), 22(4), 348–352. https://doi.org/10.7861/clinmed.2022-0166
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